METHYL 3,4-DIHYDROXY-5-METHOXYBENZOATE

Name	methyl 3,4-dihydroxy-5-methoxybenzoate
Synonyms	M3OMG Bifendate-005 Tryptophan-007 RARECHEM AL BF 0702 Methyl 3-methoxy-4,5-dihydroxybenzoate METHYL 3,4-DIHYDROXY-5-METHOXYBENZOATE methyl 3,4-dihydroxy-5-methoxybenzoate 3,4-Dihydroxy-5-methoxy methyl benzoate 3,4-Dihydroxy-5-Methoxybenzoic Acid Methyl Ester 3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER Benzoic acid, 3,4-dihydroxy-5-methoxy-, methyl ester Benzoic acid, 3,4-dihydroxy-5-Methoxy-, Methyl ester
CAS	3934-86-9
InChI	InChI=1/C9H10O5/c1-13-7-4-5(9(12)14-2)3-6(10)8(7)11/h3-4,10-11H,1-2H3

Molecular Formula	C9H10O5
Molar Mass	198.17
Density	1.337g/cm³
Boling Point	391.7°C at 760 mmHg
Flash Point	160.5°C
Vapor Presure	1.07E-06mmHg at 25°C
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.567

Biological activity	Methyl 3-O-methylgallate (M3OMG) has an antioxidant effect and can protect neurons from oxidative damage.
Animal Model:	Fifty male Wistar rats (8-12 , 7-days old, 200-250 g).
Dosage:	10 and 20 mg/kg.
Administration:	I.P. for 1 week.
Result:	Mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities.
uses	intermediates of bifendate.
Production method	Use gallic acid and methanol to esterify with sulfuric acid to generate methyl 3,4, 5-trihydroxybenzoate, and then use dimethyl sulfate Etherification to prepare the product.

Last Update：2024-04-10 22:29:15

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